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Limonoids from Khaya ivorensis.

Phytochemistry. 2009 Aug 8; Zhang B, Yang SP, Yin S, Zhang CR, Wu Y, Yue JMFour limonoids, 1-O-deacetyl-6-deoxykhayanolide E (1), 1-O-deacetyl-2alpha-hydroxykhayanolide E (2), 3-acetyl-khayalactone (3), 11alpha-acetoxy-2alpha-hydroxy-6-deoxy-destigloylswietenine acetate (4), along with 12 known limonoids, were isolated from the stems of Khaya ivorensis. Their structures were elucidated on the basis of spectroscopic analysis.

(2-Pyridyl)acetone-Promoted Cu-Catalyzed O-Arylation of Phenols with Aryl Iodides, Bromides, and Chlorides.

J Org Chem. 2009 Aug 12; Zhang Q, Wang D, Wang X, Ding KEmploying (2-pyridyl)acetone as a new supporting ligand, the copper-catalyzed coupling reactions of aryl chlorides, aryl bromides, and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. This reaction displays great functional groups compatibility and excellent reactive selectivity.

Direct Palladium-Catalyzed Arylations of Aryl Bromides with 2/9-Substituted Pyrimido[5,4-b]indolizines.

J Comb Chem. 2009 Jul 31; Jiang M, Li T, Meng L, Yang C, Xie Y, Ding JC-5 arylated 2/9-substituted pyrimido[5,4-b]indolizines were synthesized via palladium-catalyzed direct arylation. A variety of substituents on both pyrimido[5,4-b]indolizines and aryl/heteroaryl bromides are tolerated, providing rapid access to substituted pyrimido[5,4-b]indolizines in good to excellent yields.

[Lignans from stems of Sambucus williamsii]

Zhongguo Zhong Yao Za Zhi. 2009 May; 34(10): 1225-7Ouyang F, Liu Y, Xiao H, Yu H, Wang N, Yao XOBJECTIVE: To study the chemical constitutents of the 60% ethanol extract of the stems of Sambucus williamsii. METHOD: Compounds were isolated and purified by Diaion D101, silica gel,Sephadex LH-20, ODS column chromatography and preparative HPLC. Their structures were identified by spectroscopic methods. RESULT: Seven lignans were isolated and identified as erythro-guaiacylglycerol-beta-O-4'-sinapyl ether (1), 1-( 4'-hydroxy-3'-methoxyphenyl) -2- [4"-( 3-hydroxypropyl) -2", 6"-dimethoxyphenoxy] propane-1,3-diol (2), isolariciresinol (3), burselignan (4), lyoniresinol (5), 5-methoxy-isolariciresinol (6), cycloolivil (7). CONCLUSION: All these compounds were obtained from this genus for the first time.

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