Effects Of Sarcandra Glabra Extract

To study the protective effect of Sarcandra glabra extract (SGE) on immune system in restrained mice.

METHOD:
The male C57BL/6 mice were randomly divided into normal control group, stress control group, 125, 500 mg x kg(-1) SGE group. The spleen lymphocyte suspensions of each group were prepared. The parameters of spleen T cells subsets, NK cell and NKT cell proportion and number was detected by Flow cytometry.

RESULT:
SGE regulated the balance of T cell subsets, increased the percent of NK cells and NKT cell proportion and number in restrained mice.

CONCLUSION:
SGE has immunologic protective effect in restrained mice probably via the amelioration of immune cells proportion and number.


"Effects of Sarcandra glabra extract on immune activity in restraint stress mice"
Zhongguo Zhong Yao Za Zhi. 2009 Jan; 34(1): 100-3He R, Wang M, Li Y, Dai Y, Duan Y, Yao X, Kurihara H