Zhongguo Zhong Yao Za Zhi. 2009 Mar; 34(5): 512-4Liang ACarrageenan is a collective term for polysaccharides prepared by alkaline extraction from red seaweed (Rhodophycae). Different carrageenans are widely used as food and medicinal ingredients and applied in chemical and biochemical researches. The studies in recent years showed that long-term administration of carrageenan in various animals can cause intestine mucous membrane damage or ulcerous colonitis, and produce or promote tumor growth. It is necessary to perform more epidemiological and essential studies to evaluate the safety of Carrageenan.

Zhongguo Zhong Yao Za Zhi. 2009 Mar; 34(5): 567-70Liu A, Xu L, Zou ZOBJECTIVE: To isolate and identify chemical constituents of Uvaria tonkinensis var. subglabra. METHOD: The column chromatographic techniques were applied to isolate constituents, and their structures were elucidated by means of spectral data analysis including 1D and 2D NMR, IR and MS techniques. RESULT: Seven compounds were isolated and identified as subglain C (1), beta-senepoxide (2) , 2, 4-dioxohexahydro-1, 3-diazepin (3), kaempferol-3, 7-di-O-alpha-L-rhamnoside (4), anolobine (5), (-)-lyoniresinol (6) and schizandriside (7). CONCLUSION: Compound 1 was the new natural product; compounds 2-7 were isolated for the first time from U. tonkinensis var. subglabra.

Bull Exp Biol Med. 2009 Mar; 147(3): 323-7Epstein OI, Dygai AM, Sergeeva SA, Zhdanov VV, Khrichkova TY, Stavrova LA, Zyuz'kov GN, Udut EV, Simanina EVThe possibility of using ultralow-dose cyclophosphamide for reducing the myelotoxicity of cyclophosphamide, injected in the maximum permissible dose, was studied in mice. Combined treatment by the cytostatic and its ultralow-dose preparation led to a lesser suppression of the erythroid, lymphocytic, and particularly granulocytic hemopoiesis stems. This effect is explained by stimulation of the secretory activity of hemopoiesis-inducing microenvironment and hence, of the functional activity of granulocytopoiesis under the effect of ultralow-dose cyclophosphamide.

Zhongguo Zhong Yao Za Zhi. 2009 Mar; 34(5): 564-6Wang W, Wang Z, Gao H, Hong YOBJECTIVE: To establish the quality standards of roasted ginger and charry ginger prepared from dried ginger. METHOD: The basic quality information of roasted ginger and charry ginger investigated by analysis of marketed samples. Ten batches of two roasted ginger and charry ginger were prepared in medium-scale from four main growth places by the processed criterion. The quality information includes contents of ash, acid-insoluble ash, water-soluble extract and 6-gingerol. The content of 6-gingerol were determined by HPLC method. RESULT: The contents of total ash, acid-insoluble ash and water-soluble extract in processed ginger from medium-scale production were 6.3% - 7.0%, 0.3% - 0.7% and 22.11% - 41.61%, and that in charry ginger were 5.0% - 6.0%, 0.4 - 0.6 % and 20.94% - 44.92%, respectively. The contents of 6-gingerol in roasted ginger from medium-scale production and market samples were 1.05 -5.34 mg x g(-1) and 1.01-4.81 mg x g(-1), and those indexes in charry ginger were 0.43-3.81 mg x g(-1) and 0.44-3.07 mg x g(-1), respectively. Total ash, acid-insoluble ash and water-soluble extract of the two ginger processed products had no obvious difference in batch-to-batch,but the contents of 6-gingerol were closely related to their growth places. CONCLUSION: The above data provide evidences for production and quality control of ginger processed products.