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[Chemical constituents of flavonoids from rhizome of Sophora tonkinensis]

Zhongguo Zhong Yao Za Zhi. 2009 Feb; 34(3): 282-5Li X, Yan H, Pang X, Sha N, Hua H, Wu L, Guo DOBJECTIVE: To study the chemical constituents of the flavonoids from Sophora tonkinensis. METHOD: The compounds were isolated by chromatography on silica gel, Sephadex LH-20 column and identified by spectroscopic analysis. RESULT: Eight compounds were isolated and their structures were identified as tonkinochromane I (1), glabrol (3), lupinifolin (2), tonkinensisol (4), 8-C-prenylkaempferol (5), 7,2'-dihydroxy-4'-methoxy-isoflavanol (6), formononetin (7), and genistein (8), respectively. CONCLUSION: Compound 1 was a new compound. And compound 6 was firstly isolated from the genus Sophora. Compounds 2, 3 and 5 were isolated from S. tonkinensis for the first time.

[Study on Diels-Alder type adducts from stem barks of Morus yunanensis]

Zhongguo Zhong Yao Za Zhi. 2009 Feb; 34(3): 286-90Cui X, Chen H, Chen ROBJECTIVE: To isolate and identify the Diels-Alder type adducts from stem barks of Morus yunanensis. METHOD: The compounds were isolated and purified by silicagel, Sephadex LH-20 and RP-18 colum chromatography. Their chemical structures were elucidated on the basis ofphysicochemical properties and spectral data. RESULT: Nine compounds were isolated and identified as: kuwanon G (1), sanggenol M (2), mulberrofuran J (3), guangsangon B (4), resveratrol (5), kuwanon X (6), kuwanon P (7), mulberrofuran O (8), mulberrofuran Q (9). CONCLUSION: All the compounds are isolated from the plant for the first time, and compounds 4, 5 have anti-inflammation activities with inhibitory ratios of 57.3%, 50.5% respectively at a concentration of 10 microg mL(-1).

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