• Imagen 1

Thinking out of the national box: what is there to learn?

Homeopathy. 2009 Jul; 98(3): 135-6Güthlin C

[Studies on chemical constituents from herbs of Viola yedoensis]

Zhongguo Zhong Yao Za Zhi. 2009 May; 34(9): 1114-6Huang J, Yang J, Xue Q, Yu L, Zhang DOBJECTIVE: To study the chemical constituents of the whole plant of Viola yedoensis. METHOD: The compounds were isolated by various chromatographic techniques and their structures were elucidated by their physicochemical properties and the analysis of their spectral data. RESULT: Seven compounds were isolated and identified as esculetin (1), isoscopoletin (2), 6-hydroxymethyl-3-pyridinol (3),5,5-bi (6,7-dihydroxycoumarin) (4), 6,6,7,7-tetrahydroxy-5,8-bicoumarin (5), loliolide (6), dehydrololiolide (7). CONCLUSION: Compounds 2-7 were isolated from V. yedoensis for the first time.

Monoterpenes from Paeonia albiflora and Their Inhibitory Activity on Nitric Oxide Production by Lipopolysaccharide-Activated Microglia.

J Nat Prod. 2009 Aug 19; Duan WJ, Yang JY, Chen LX, Zhang LJ, Jiang ZH, Cai XD, Zhang X, Qiu FEleven new monoterpenes, paeonidangenin (1), paeonidanin A (2), paeonidanin B (3), paeonidanin C (4), paeonidanin D (5), paeonidanin E (6), paeoniflorone (7), 4-O-methylbenzoylpaeoniflorin (8), 4-O-methylgalloylpaeoniflorin (9), 4-O-methyldebenzoylpaeoniflorin (10), and 4-O-methylalbiflorin (11), were isolated from the 60% ethanol extract of the roots of Paeonia albiflora. Their structures were determined primarily on the basis of 1D and 2D NMR techniques and MS studies. Paeonidanins D (5) and E (6) are unprecedented examples of "cage-like" monoterpene dimers. The inhibitory effects of the isolated compounds on nitric oxide production by lipopolysaccharide (LPS)-activated N9 microglia were evaluated.

;