Two New Unprecedented Acetonyl-Bearing Sesquiterpenes from the Hainan Sponge Dysidea fragilis.

Chem Biodivers. 2009 Jun 23; 6(6): 858-863Yu ZG, Li J, Li ZY, Guo YWTwo new acetonyl-bearing sesquiterpenes, dysifragilisins A and B (1 and 2, resp.), have been isolated from the Hainan marine sponge Dysidea fragilis. The structures of the new compounds were elucidated on the basis of detailed spectroscopic analyses and by comparison of their NMR data with those of structurally related compounds. A plausible biogenetic pathway is proposed for the origin of compounds 1 and 2.