[Chemical constituents of flavonoids from rhizome of Sophora tonkinensis]

Zhongguo Zhong Yao Za Zhi. 2009 Feb; 34(3): 282-5Li X, Yan H, Pang X, Sha N, Hua H, Wu L, Guo DOBJECTIVE: To study the chemical constituents of the flavonoids from Sophora tonkinensis. METHOD: The compounds were isolated by chromatography on silica gel, Sephadex LH-20 column and identified by spectroscopic analysis. RESULT: Eight compounds were isolated and their structures were identified as tonkinochromane I (1), glabrol (3), lupinifolin (2), tonkinensisol (4), 8-C-prenylkaempferol (5), 7,2'-dihydroxy-4'-methoxy-isoflavanol (6), formononetin (7), and genistein (8), respectively. CONCLUSION: Compound 1 was a new compound. And compound 6 was firstly isolated from the genus Sophora. Compounds 2, 3 and 5 were isolated from S. tonkinensis for the first time.