[Study on Diels-Alder type adducts from stem barks of Morus yunanensis]

Zhongguo Zhong Yao Za Zhi. 2009 Feb; 34(3): 286-90Cui X, Chen H, Chen ROBJECTIVE: To isolate and identify the Diels-Alder type adducts from stem barks of Morus yunanensis. METHOD: The compounds were isolated and purified by silicagel, Sephadex LH-20 and RP-18 colum chromatography. Their chemical structures were elucidated on the basis ofphysicochemical properties and spectral data. RESULT: Nine compounds were isolated and identified as: kuwanon G (1), sanggenol M (2), mulberrofuran J (3), guangsangon B (4), resveratrol (5), kuwanon X (6), kuwanon P (7), mulberrofuran O (8), mulberrofuran Q (9). CONCLUSION: All the compounds are isolated from the plant for the first time, and compounds 4, 5 have anti-inflammation activities with inhibitory ratios of 57.3%, 50.5% respectively at a concentration of 10 microg mL(-1).